African Congress for Clinical Trials
Lambaréné, 10-14 November 2019 (2nd edition)
Clinical trial in Sub-saharan Africa : Challenge or Opportunity ?
The CERMEL Tuberculosis Laboratory was established in 2009. Since then, it has acquired a great expertise and experience in performing microscopy (ZN and fluorescence), gold-standard diagnosis based on culture on liquid (MGIT) and solid (LJ) media, as well as Drug Sensitivity Testing (DST) and molecular diagnosis, such as Gene Xpert and Line Probe Assays (LPA).
The laboratory is currently conducting an epidemiological and longitudinal cohort study on tuberculosis in Moyen-Ogooué region.
As part of activities with Gabon National TB Control Programme (PNLT), the laboratory is a member of the national network of reference laboratories, meaning that we perform routine diagnosis for regional and national hospitals.
Moreover, the TB Laboratory provides training to national and international students and professionals.
CERMEL Microbiology Laboratory analyzes bacteriological samples from clinical trials conducted at the center, as well as from the Albert Schweitzer Hospital. In parallel to such routine analyses, our research focusses on the high prevalence of pathogens resistent to antibiotics, including third generation cephalosporins.
The Laboratory is also focused on Staphylococcus aureus epidemiology and pathogenesis; we have shown for instance that transmission, colonization and bacterial virulence factors of S. aureus are different in African populations compared to Europeans.